The Lead Detect Prize seeks to accelerate the development of next-generation point-of-care blood lead testing technology. The challenge, on behalf of the Centers for Disease Control and Prevention, will advance blood lead test solutions by providing funding and expertise while fostering collaboration and partnership. Phase 1 awarded five winners an equal share of a $150,000 prize pool. Phase 1 winners were also exclusively invited to enter Phase 2 and participated in a virtual accelerator. Three Phase 2 winners were awarded a share of a $850,000 Phase 2 prize pool.